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Masato Fujioka Selected Research

Pendred syndrome

5/2020A phase I/IIa double blind single institute trial of low dose sirolimus for Pendred syndrome/DFNB4.
6/2019Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome.
1/2017Cochlear Cell Modeling Using Disease-Specific iPSCs Unveils a Degenerative Phenotype and Suggests Treatments for Congenital Progressive Hearing Loss.
12/2013[Current status and perspectives of the research in Pendred syndrome].

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Masato Fujioka Research Topics

Disease

14Hearing Loss (Hearing Impairment)
11/2021 - 04/2010
4Pendred syndrome
05/2020 - 12/2013
3Sensorineural Hearing Loss
06/2022 - 01/2012
2Tympanic Membrane Perforation
12/2021 - 08/2021
2Wounds and Injuries (Trauma)
08/2021 - 01/2013
2Neoplasms (Cancer)
01/2021 - 12/2019
2Deafness (Deaf Mutism)
01/2021 - 01/2017
2Neurofibromatosis 2 (Neurofibromatosis Type II)
01/2020 - 12/2019
2Tinnitus
02/2014 - 05/2013
2Seasonal Allergic Rhinitis (Hay Fever)
11/2012 - 01/2012
2Allergic Rhinitis
11/2012 - 01/2012
2Asthma (Bronchial Asthma)
11/2012 - 01/2012
1Otitis Media with Effusion
01/2022
1Congenital Cholesteatoma
01/2022
1Otitis Media
08/2021
1Otosclerosis
02/2021
1Neurodegenerative Diseases (Neurodegenerative Disease)
05/2020
1Neurilemmoma (Schwannoma)
12/2019
1Wolfram Syndrome (Syndrome, Wolfram)
01/2016
1Noise-Induced Hearing Loss (Acoustic Trauma)
11/2015
1Necrosis
02/2015
1Mitochondrial Diseases (Mitochondrial Disease)
01/2014
1Goiter
12/2013
1Nasal Obstruction
11/2012

Drug/Important Bio-Agent (IBA)

2Sirolimus (Rapamycin)FDA Link
05/2020 - 06/2019
2VaccinesIBA
01/2020 - 12/2019
2Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
01/2020 - 12/2019
2Interleukin-6 (Interleukin 6)IBA
01/2014 - 04/2010
2pranlukastIBA
11/2012 - 01/2012
1Pharmaceutical PreparationsIBA
06/2022
1Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
12/2021
1GelatinIBA
12/2021
1Thymidine Monophosphate (TMP)IBA
12/2021
1Fibrin Tissue Adhesive (Fibrin Sealant)IBA
12/2021
1Anti-Bacterial Agents (Antibiotics)IBA
08/2021
1Durapatite (Hydroxylapatite)IBA
02/2021
1Phosphotransferases (Kinase)IBA
01/2021
1ConnexinsIBA
01/2021
1Proteins (Proteins, Gene)FDA Link
01/2021
1Connexin 26IBA
01/2021
1Protein Subunit VaccinesIBA
12/2019
1Bevacizumab (Avastin)FDA Link
12/2019
1Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
12/2019
1AnionsIBA
01/2017
1Mitochondrial DNA (mtDNA)IBA
01/2017
1wolframin proteinIBA
01/2016
1Protein Isoforms (Isoforms)IBA
11/2015
1Adenosine Triphosphate (ATP)IBA
02/2015
13-nitropropionic acidIBA
01/2014
1IodidesIBA
12/2013
1Amyloid Precursor Protein Secretases (beta-Secretase)IBA
01/2013
1Biological ProductsIBA
11/2012
1Eosinophil Cationic ProteinIBA
11/2012
1leukotriene D4 receptor (cysteinyl leukotriene receptor)IBA
11/2012
1AllergensIBA
11/2012
1SteroidsIBA
01/2012
1Leukotriene Antagonists (Leukotriene Receptor Antagonists)IBA
01/2012
1CytokinesIBA
04/2010

Therapy/Procedure

9Therapeutics
11/2021 - 04/2010
1Conservative Treatment
01/2022
1Tympanoplasty
08/2021
1Mastoidectomy
08/2021
1Stapes Surgery (Stapedectomy)
02/2021
1Prostheses and Implants (Prosthesis)
02/2021
1Oral Administration
05/2020
1Operative Surgical Procedures
01/2018
1Activities of Daily Living (ADL)
05/2013
1Injections
01/2012